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Dirk Henrich

Dirk Henrich

Dirk Henrich

Head, Research Laboratory
Department of Trauma-, Hand- & Reconstructive Surgery, Johann-Wolfgang-Goethe-University
+49 (0)69 6301 7110 (Office)
d.henrich [at]
Goethe University Hospital
60590 Frankfurt/Main


Research Focus

Dr. Henrich heads the Research Laboratories of the Department of Trauma-, Hand- and Reconstructive Surgery, at the Johann Wolfgang Goethe University in Frankfurt am Main, Germany. In that role he works closely with the Frankfurt Initiative for Regenerative Medicine on a variety of different projects related to musculoskeletal regeneration.

Dr. Henrich’s research focuses on the interplay between progenitor and inflammatory cell behavior in musculoskeletal tissues during trauma.


Biology 1989 - 1994 Goethe University, Frankfurt an Main, Germany
Diploma Thesis 1994 “Change of motility of human fibroblasts during psoriasis”
Institute for Kinematic Cell Research (Supervisor: Prof. Bereiter-Hahn)
Goethe University, Frankfurt Main, Germany
Doctoral Thesis 1995 “Influence of Vitamin-A on function of the peripheral immune system”
Supervisor: Prof. Dr. Träger
Gustav Embden Zentrum für Biologische Chemie, Frankfurt Main, Germany
Postdoctoral 1998 “Role and Function of polymorphoneucleated leukocytes during human peritonitis”
Supervisor: Prof. Encke, Dr. Holzer
Department of Abdominal Surgery, Goethe University, Frankfurt Main, Germany
Head of Laboratory 2001 Department of Trauma-, Hand- and Reconstructive Surgery
Director: Prof. I. Marzi
Goethe University, Frankfurt Main, Germany


Selected Publications/ Presentations

The following are selected publications. Click here for a complete list of publications.

  • Trauma-activated polymorphonucleated leukocytes damage endothelial progenitor cells: probable role of CD11b/CD18-CD54 interaction and release of reactive oxygen species. Henrich, D., Zimmer, S., Seebach, C., Frank, J., Barker, J., and Marzi, I. Shock 36:216-222. (2011).
  • In vitro manipulation of endothelial progenitor cell adhesion to vascular endothelium and extracellular matrix by the phorbol ester PMA. Artif. Cells Blood Substit. Immobil. Biotechnol. Powerski, M., Henrich, D., Sander, A., Teiler, A., and Marzi, I. 39:214-222. (2011).
  • CD133+CD34+ stem cells are mobilized after musculoskeletal surgery and target endothelium activated by surgical wound fluid. Powerski, M. J., Henrich, D., Sander, A., Wastl, D., Ludwig, K., and Marzi, I. Langenbecks Arch. Surg. 396:379-387. (2011).
  • RIA reamings and hip aspirate: a comparative evaluation of osteoprogenitor and endothelial progenitor cells. Henrich, D., Seebach, C., Sterlepper, E., Tauchmann, C., Marzi, I., and Frank, J. Injury 41 Suppl 2:S62-S68. (2010).